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The intracellular targets of motion of metronidazole on anaerobes are mainly not known. The five-nitro team of metronidazole is lowered by metabolically Energetic anaerobes, and studies have shown which the minimized form of the drug interacts with bacterial DNA.
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METROGEL-VAGINAL affords negligible jnetoto peak serum concentrations and systemic publicity (AUCs) of metronidazole as compared to five hundred mg oral metronidazole dosing. Despite the fact that these lower levels of publicity are more unlikely to supply the widespread reactions found with oral metronidazole, the opportunity of these and various reactions cannot be excluded presently.
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